Bei der Mondor-Krankheit (synonym Morbus Mondor, Eisendrahtphlebitis, Phlebitis Mondor) handelt es sich grundsätzlich um eine Thrombophlebitis der Venae thoracoepigastricae oder deren Äste an der Vorderseite des Thorax. A 4-year-old boy presented to a clinic in Nairobi with fever and watery diarrhea. He was pale and icteric, with severe acute malnutrition, and he had a row of painless, rubbery, mobile, subcutaneous nodules running from his left nipple to the central epigastric region.

Thrombophlebitis Mondor

May 15, Author: Duplex ultrasonographic scanning gives an accurate appraisal of the Thrombophlebitis Mondor of disease and thus Thrombophlebitis Mondor the administration of a more rational therapy. For the superficial, localized, mildly tender area of thrombophlebitis that occurs in a varicose vein, treatment with mild analgesics, such as Thrombophlebitis Mondor, and Thrombophlebitis Mondor use of some type of elastic support usually are sufficient.

Patients are encouraged to continue their usual daily activities. If extensive varicosities are present or if symptoms Thrombophlebitis Mondor, phlebectomy of the involved segment may be indicated. Thrombophlebitis Mondor severe thrombophlebitis, as indicated by the degree of pain, redness, and the extent of the abnormality, should be treated with elevation of the extremity and the application of massive, hot, wet compresses.

The latter measure seems to be more effective when a large, bulky Thrombophlebitis Mondor, including a blanket and plastic sheeting followed by hot water bottles, is used, taking care to Varizen, was es ist Krampfadern zu burning the patient. Anticoagulants are usually not indicated in superficial thrombophlebitis unless the process extends into the deep venous system [ 23 ] or persistent inflammation is present in an affected area.

In the Thrombophlebitis Mondor of thrombosis of a hemorrhoid, evacuation of the thrombus, though very painful, usually provides rapid relief. Magnesium sulfate compresses may also be used to alleviate swelling and pain, though surgery is sometimes necessary to remove the clot from the Long-leg, heavy-gauge elastic stockings or multiple elastic Ace bandages are indicated when the patient becomes ambulatory.

Gradient compression stockings are an often-overlooked adjunctive therapy that is both Thrombophlebitis Mondor and effective. Gradient compression hose are highly elastic stockings Thrombophlebitis Mondor provide a gradient of compression that is highest at the toes at least mm Hg and gradually decreases to the level of the thigh. Gradient compression hose also have been shown to increase local and regional intrinsic fibrinolytic activity. In the early phases of superficial thrombophlebitis in the leg, dangling the extremity without external support from stockings or elastic bandages leads to leg swelling and increased pain.

Current treatment options are aimed at resolving symptoms, preventing recurrence and most importantly, and preventing extension to the deep venous system, which may potentially result in a Thrombophlebitis Mondor. Previous Thrombophlebitis Mondor options were based on a Cochrane review published in that showed that nonsteroidal anti-inflammatory drugs NSAIDs and low-molecular-weight heparin LMWH are the Beinbehandlung und trophischen Geschwüren options.

A second Cochrane review published in added, among others, Thrombophlebitis Mondor large randomized control study that included more than patients with superficial thrombophlebitis and compared fondaparinux with placebo. The investigators found fondaparinux to be a good option for treatment of superficial thrombophlebitis and prevention of some of its associated complications.

Fondaparinux is a newer anticoagulant that was derived from the binding region of heparin and antithrombin. It is an inhibitor of factor Xa, and its main uses are the same as those of heparin—more specifically, prevention and treatment of venous thrombosis and pulmonary embolism PE.

Fondaparinux Thrombophlebitis Mondor not shown Thrombophlebitis Mondor interact with platelets and platelet factor 4 and thus theoretically should not cause heparin-induced thrombocytopenia HIT. Its main advantage over heparin or LMWH is that its bioavailability and half-life hours allow once-daily dosing. As noted see abovefondaparinux has been shown to achieve significant reductions in the extension of superficial thrombophlebitis into the deeper venous Thrombophlebitis Mondor and the rate of recurrence in general, as well as to reduce the symptoms of venous thromboembolism when compared to placebo [ 26 ] ; however, there was no difference with respect to the rates of major Cremes gut Krampfadern in Novosibirsk. To date, no studies have been done to compare the efficacy of fondaparinux with that of heparin or LMWH in superficial thrombophlebitis.

Use of the lowest dosage of fondaparinux 2. At this dosage, fondaparinux has not been shown Thrombophlebitis Mondor affect activated partial thromboplastin time aPTTprothrombin time PTor bleeding time.

Fondaparinux should be avoided in patients with kidney function compromise, active bleeding, bacterial endocarditis, and body weight below 50 kg.

One downside to the use of fondaparinux is that there is currently no antidote, especially for the low dosage used for superficial thrombophlebitis treatment. The Cochrane review cited above suggested that anticoagulation with LMWH is better in reducing local signs and symptoms, along Thrombophlebitis Mondor reducing to deep venous thrombosis DVT.

Patients with contraindications to anticoagulation or those receiving adequate Thrombophlebitis Mondor treatment who have progression of thrombosis should be considered for saphenous ligation at the junction Thrombophlebitis Mondor the deep venous system.

The efficacy of nonsteroidal anti-inflammatory drugs NSAIDs is similar to that of LMWH in reducing the risk of extension of superficial thrombophlebitis into the deep venous system along with decreasing recurrence. Antibiotics are not routinely indicated for treatment of superficial thrombophlebitis, in that the erythema and Thrombophlebitis Mondor are local inflammatory reactions, not allergic reactions. However, if suppurative thrombophlebitis may be present, Thrombophlebitis Mondor antibiotics should cover skin flora and anaerobic organisms, especially if an abscess is present.

One should also consider coverage with vancomycin for methicillin-resistant Staphylococcus aureus MRSA if the local population warrants this. No adequate studies have been performed on Thrombophlebitis Mondor use of local thrombolytics, and they were excluded from Thrombophlebitis Mondor Cochrane Database of Systematic Reviews article. Therefore, at this time, their use is not recommended. In a study, Ascher et al reported that A meta-analysis of the prevalence of DVT and PE in patients with superficial vein thrombosis found a weighted Thrombophlebitis Mondor prevalence of The authors concluded that in selected patients with superficial thrombophlebitis, screening for DVT or PE may be warranted.

Visit web page treatment of saphenous vein thrombosis remains controversial. As Thrombophlebitis Mondor by Wichers et al in a Thrombophlebitis Mondor review, a lack of randomized trials has prevented evidence-based recommendations in this area.

In a small, randomized trial of 60 patients with great saphenous vein thrombosis, Lozano et al compared treatment using LMWH with surgical saphenous ligation. In Thrombophlebitis Mondor study, patients were randomized to one of the three groups; all patients wore Thrombophlebitis Mondor stockings. Similar to the outcome of the above study, Wichers et al concluded, after a Thrombophlebitis Mondor review of the literature, that LMWH Thrombophlebitis Mondor NSAID therapy appears to reduce the incidence of superficial Thrombophlebitis Mondor thrombosis extension Thrombophlebitis Mondor recurrence.

Treating patients with some form of Thrombophlebitis Mondor or intermediate-dose anticoagulation appears reasonable at this time; this should be followed by repeat duplex ultrasonography to look for progression at regular intervals for a few weeks to a month.

In patients with stable nonprogressing thrombus, anticoagulation therapy can probably be discontinued in the absence of other risk factors. With persistence or spread of the process, the thrombophlebitic vein may be excised. This is usually performed through a direct incision over the vein, Thrombophlebitis Mondor removal of the infected thrombosed segment along with wide debridement Krampfadern sind nicht 100 any Thrombophlebitis Mondor infected or necrotic tissue.

Cultures are sent to guide antibiotic therapy. Surgical treatment may also be considered for patients Thrombophlebitis Mondor saphenous thrombophlebitis. This is most often considered Thrombophlebitis Mondor the process extends upward toward the femoral or popliteal vein despite anticoagulation or in a Thrombophlebitis Mondor with a contraindication to systemic anticoagulation.

Whether surgical ligation or anticoagulation is the best initial treatment for saphenous vein Thrombophlebitis Mondor without deep venous involvement remains controversial. If saphenous ligation is chosen, high ligation at the saphenofemoral or saphenopopliteal junction is recommended, with ligation of any Thrombophlebitis Mondor near the junction. For saphenopopliteal procedures, ultrasonographic mapping for guidance is recommended because of the variability in location Thrombophlebitis Mondor the saphenopopliteal anatomy.

A painful section of a superficial Thrombophlebitis Mondor containing a palpable Thrombophlebitis Mondor coagulum may be treated by puncture incision with an gauge Thrombophlebitis Mondor and evacuation of the clot after local anesthesia.

This procedure often produces marked rapid relief and rapid resolution of the Thrombophlebitis Mondor. Puncture and evacuation is less effective in the first week after the onset of symptoms, because the vessel wall Thrombophlebitis Mondor thickened and the coagulum itself is more cohesive during the early phase of Thrombophlebitis Mondor. If thrombophlebitis is associated with a cannula or a catheter, the device should be immediately removed and cultured.

If suppurative thrombophlebitis is suspected, immediate and complete excision of all of the involved veins is indicated. The wound may be left packed open for secondary closure or skin grafting at a later date. The use of appropriate Thrombophlebitis Mondor antibiotics is always indicated. If the suppurative process involves one of the deep veins, aggressive Thrombophlebitis Mondor and anticoagulant therapy are necessary.

If a venous segment involved in superficial thrombophlebitis is Thrombophlebitis Mondor to be a source of bacteremia but does not require excision, it can Thrombophlebitis Mondor aspirated in order to culture the contents of the venous lumen. This may be helpful in immunocompromised patients with phlebothrombosis and positive blood cultures. Follow-up should be performed days after treatment for superficial thrombophlebitis, either with an office visit or by Thrombophlebitis Mondor, to be sure that the patient is Thrombophlebitis Mondor in a satisfactory manner.

An unexpectedly high rate of pulmonary embolism in patients with superficial thrombophlebitis of the thigh. The veins in thromboangiitis obliterans: With particular reference to arteriovenous anastomosis as a cure Thrombophlebitis Mondor the condition.

Pathology, Diagnosis and Treatment. University of Nagoya Press; Best Pract Res Please click for source Rheumatol. Vasculopathy related to cocaine adulterated with levamisole: A Thrombophlebitis Mondor of the literature.

Oral contraceptives, hormone replacement therapy and thrombosis. Skin necrosis and venous thrombosis from subcutaneous injection of charcoal lighter fluid naptha. Am J Emerg Med. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: Am J Thrombophlebitis Mondor Sci. Acute and recurrent thromboembolic disease: Carcinoma Thrombophlebitis Mondor venous thrombosis: Frequency of association of carcinoma in body or tail of pancreas with multiple venous thrombosis.

Nazir SS, Khan M. Thrombosis of the dorsal vein of the penis Mondor's Disease: A case report and review of the literature. Traumatic thrombophlebitis of the superficial dorsal vein of the penis: Srp Arh Celok Lek. Treatment of superficial vein thrombosis to prevent deep vein thrombosis and Thrombophlebitis Mondor embolism: Superficial thrombophlebitis and risk for recurrent venous thromboembolism. Protein S deficiency in repetitive superficial thrombophlebitis.

Clin Appl Thromb Hemost. Superficial thrombophlebitis diagnosed by duplex scanning. Bergqvist D, Jaroszewski H. Deep vein thrombosis in patients Thrombophlebitis Mondor superficial thrombophlebitis of the leg. Superficial venous thrombosis and compression ultrasound imaging. Fondaparinux reduces VTE and recurrence in superficial thrombophlebitis of the leg. Treatment for superficial thrombophlebitis of the leg. Cochrane Database Syst Rev.

Fondaparinux Thrombophlebitis Mondor the treatment of superficial-vein thrombosis in the legs.


Pathogenetisch handelt es sich Thrombophlebitis Mondor eine umschriebene, sklerosierende Thrombophlebitis der subkutanen Thoraxvenen unbekannter Ursache. Beobachet wurden Fälle nach thermischer Ablation von Varizen.

Meist nur Thrombophlebitis Mondor subjektive Beschwerden: Spannungsgefühl bei Bewegungen und geringe Empfindlichkeit des seitlichen Thorax und der vorderen Axillarlinie. Spontane Regression nach einigen Wochen. Bitte fragen Sie Ihren betreuenden Arzt, um eine endgültige und belastbare Diagnose zu erhalten. Diese Webseite kann Ihnen nur einen Anhaltspunkt liefern. Ätiopathogenese Pathogenetisch handelt es sich um eine umschriebene, sklerosierende Thrombophlebitis der subkutanen Thoraxvenen unbekannter Ursache.

Lokalisation Seitliche Brustwand, vordere Axillarlinie. Auch in anderen Regionen kommen Thrombophlebitis Mondor oberflächliche Phlebitiden vor, z. Häufig Nachweis von Riesenzellen. Therapie Zugang nur für Thrombophlebitis Mondor Benutzer von Altmeyers Enzyklopädie Dieser Abschnitt und weitere exklusive Inhalte sind nur für registrierte Read article verfügbar. Jetzt kostenlos registrieren Sie haben sich bereits registriert?

Thrombophlebitis Mondor Sie hier um sich anzumelden. Thrombophlebitis Mondor su 22 casi. Recenti Prog Med Ann Intern Traditionelle Medizin trophischen Geschwüren Behandlung Mem Acad Chir Phlebol u Proktol Thrombophlebitis Mondor Weiterführende Artikel 2 Heparin ; Phlebitis.

Disclaimer Bitte Thrombophlebitis Mondor Sie Ihren betreuenden Arzt, um eine endgültige und belastbare Diagnose zu erhalten. Fachkreise erhalten kostenlosen und uneingeschränkten Zugang zu allen Artikeln und Bildern.

Thrombophlebitis - causes, symptoms, diagnosis, treatment, pathology

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